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Every episode
Health Optimization Medicine Podcast
30 episodes
Is Your Cellular Membrane Leaking the Fuel That Keeps You Going? (Why NAD+ Isn't Enough) | HOMe #022
Ep 22 · Aug 12, 2026 · 24 min
In this episode of the Health Optimization Medicine Podcast, Dr. Scott Sherr, Dr. Ted Achacoso, Dr. Allen Bookatz, and Jodi Duval explore one of the most overlooked causes of declining cellular energy: the structural breakdown of the mitochondrial membrane. While many people invest in premium longevity supplements like NAD+, NMN, and CoQ10 to improve energy production, emerging research suggests these compounds cannot overcome a damaged mitochondrial membrane. The team explains how age-related p…
Dr. Dominic D'Agostino Explains What Ketones Actually Do to Your Body | HOMe Podcast #021
Ep 21 · Aug 5, 2026 · 53 min
In this episode of the Health Optimization Medicine Podcast, Dr. Scott Sherr sits down with Dr. Dominic D'Agostino, the premier researcher in ketogenic metabolic therapies. Moving past the mainstream fads of keto ice cream and internet trends, they break down how exogenous ketones actually impact cellular energy, cardiovascular health, and environmental stress. From the liver toxicity associated with certain high-dose ketone esters to the hidden vasodilatory superpowers of L-BHB, this discussion…
Metformin is Poisoning Your Cells | HOMe Podcast #020
Ep 20 · Aug 3, 2026 · 19 min
In this episode of the Health Optimization Medicine Podcast, Dr. Ted Achacoso, Dr. Scott Sherr, Dr. Allen Bookatz, Jodi Duval, and Dr. Jup Kuipers take a deep dive into the shocking new 21-year pre-diabetes follow-up study (DPPOS) published in the Journal of the American Medical Association on June 15, 2026. Moving past the mainstream longevity hype surrounding Metformin as an anti-aging cure-all, the faculty breaks down why chemically poisoning your enzymes is a profound mismatch for healthy, a…
The Gut-Brain-Microbiome Axis: Understanding Depression, Serotonin, & Probiotics | HOMe Podcast #019
Ep 19 · Jul 22, 2026 · 32 min
In this episode of the Health Optimization Medicine Podcast, Dr. Ted Achacoso, Dr. Scott Sherr, Dr. Allen Bookatz, Dr. Jup Kuipers, and Jodi Duval take a deep dive into the gut-brain-microbiota axis. Moving past the simplistic, pathogenic "pill-for-an-ill" approach of conventional psychiatry and the mainstream hype around over-the-counter probiotics, the faculty breaks down why establishing enteric safety must always precede biochemical optimization. Join us as we delve into: The Tripartite Axis…
Why You Can't Out-Supplement a Dysregulated Nervous System | HOMe Podcast #018
Ep 18 · Jul 15, 2026 · 27 min
In this episode of the Health Optimization Medicine Podcast, Dr. Allen Bookatz, Dr. Ted Achacoso, and Jodi Duval tackle the widespread trend of supplement fatigue. As biohacking becomes a mindset of treating symptoms with heavy stimulants and endless pills, the faculty breaks down why forcing adaptation on an exhausted system only drives the body deeper into a chronic state of inflammatory defense. From the biophysics of the Cell Danger Response (CDR1) to practical parasympathetic upregulation,…
Cellular Safety and the Dangers of Mechanical Blood Microplastic Detox | HOMe Podcast #017
Ep 17 · Jul 8, 2026 · 21 min
In this episode of the Health Optimization Medicine Podcast, our faculty, Dr. Scott Sherr, Dr. Ted Achacoso, Boomer Anderson, Dr. Allen Bookatz, and Jodi Duval, tackle the recent trend of therapeutic plasma exchange and "blood washing". Moving past the mainstream marketing of plasmapheresis as a longevity cure-all, the team breaks down why mechanical filtering is only a surface-level fix for microplastic toxicity. From the autonomic anxiety caused by biological lockdown to the clinical applicati…
The HRV Paradox: Why Tracking Your Sleep Makes It Worse | HOMe Podcast #016
Ep 16 · Jul 1, 2026 · 21 min
In this episode of the Health Optimization Medicine Podcast, the HOMeHOPe faculty (Dr. Scott Sherr, Dr. Ted Achacoso, Boomer Anderson, and Jodi Duval) tackles one of the most paradoxical trends in modern biohacking: sleep tracking. Moving past the mainstream obsession with daily device scores, the team breaks down the biochemical realities of how tracking your HRV might actually be sabotaging your sleep architecture. From the autonomic anxiety caused by digital wearables to the clinical applicat…
Decoding the Holobiont: The Ecosystem of Ecosystems | HOMe Podcast Special Episode
Ep 16 · Jun 24, 2026 · 15 min
In this special in-person roundtable recorded in Washington, D.C., the HOMeHOPe faculty sit down to decode one of the most important perspective shifts in modern health: the Holobiont. Moving away from the traditional, siloed medical model of "organology" (treating the heart, gut, and brain as isolated systems managed by different specialists), the faculty discusses why true health optimization requires viewing the human body as a complex, interconnected ecosystem of ecosystems. Join us as we de…
Bypass the Fiber Trend & Optimize Your Gut Health | HOMe Podcast #015
Ep 15 · Jun 17, 2026 · 15 min
In this episode of the Health Optimization Medicine Podcast, the core faculty (Dr. Scott Sherr, Dr. Ted Achacoso, Dr. Jup Kuipers, and Dr. Allen Bookatz) tackles one of the most misunderstood topics in modern nutrition: fiber. Moving past the mainstream trend of "fiber-maxing," the team breaks down the actual biochemical realities of how different forms of fiber interact with your unique gut microbiome. From the surprising hormonal impacts of over-consuming fiber to the rise of localized conditi…
Why Aging May Be the Root Cause of Chronic Disease | HOMe Podcast #014
Ep 14 · Jun 10, 2026 · 14 min
In this episode of the Health Optimization Medicine Podcast, the HOMeHOPe faculty, Dr. Scott Sherr, Dr. Ted Achacoso, Dr. Jup Kuipers, and Dr. Allen Bookatz reunite in person in Washington, D.C.. Moving away from traditional classifications of illness, the team breaks down a powerful paradigm shift: chronic disease and aging are not separate processes—chronic disease is aging. Drawing from the pioneering frameworks of biogerontologist Aubrey de Grey and the SENS Research Foundation, they discuss…
Health Optimization for Parenting, Pregnancy & Family Life | HOMe Podcast #013
Ep 13 · Jun 3, 2026 · 25 min
In this episode of the Health Optimization Medicine Podcast, hosts Dr. Scott Sherr and Jodi Duval come together for an intimate, parent-to-parent roundtable. As the only current parents on the HOMeHOPe faculty, they dive deep into the specific biology of preconception, pregnancy, and pediatric health optimization. Moving beyond typical disease management, they explore how to foster both psychological and cellular safety across the entire family unit. Join us as we delve into: The Masterclass Blu…
What Nobody Told You About Your Gut | HOMe Podcast #012
Ep 12 · May 27, 2026 · 33 min
In this episode of the Health Optimization Medicine Podcast, the HOMeHOPe Faculty (Dr. Scott Sherr, Dr. Allen Bookatz, Dr. Ted Achacoso, and Dr. Jup Kuipers) dive deep into the unseen world inside your stomach. Moving beyond simple probiotics, they discuss the gut as a "post-natal organ" and explore how the trillions of microbes inside you actually dictate your cravings, your mood, and your immune system. 𝗝𝗼𝗶𝗻 𝘂𝘀 𝗮𝘀 𝘄𝗲 𝗱𝗲𝗹𝘃𝗲 𝗶𝗻𝘁𝗼: •The "tripartite axis" (Gut-Brain-Enteric Micr…
The Problem with Over-Optimization in Modern Health | HOMe Podcast #011
Ep 11 · May 20, 2026 · 25 min
In this episode of the Health Optimization Medicine Podcast, Dr. Scott Sherr, Dr. Allen Bookatz, and Dr. Jup Kuipers come together live in studio in Washington, D.C. to discuss the dangers of over-optimization and the "more is better" mentality. They explore real clinical case studies of patients who inadvertently damaged their health by blindly following supplement trends. Join us as we delve into: The dangers of over-supplementing with high-dose Fish Oil and Vitamin B6. How shifting to an "Ome…
Creatine, Cellular Energy, and the Modern Stress Epidemic | HOMe Podcast #010
Ep 10 · May 13, 2026 · 26 min
In this episode of the Health Optimization Medicine Podcast, the HOMeHOPe Faculty comes together for a roundtable conversation exploring the science and clinical application of creatine. Moving beyond its reputation as just a performance supplement for "gym bros," Boomer Anderson, Dr. Scott Sherr, Dr. Allen Bookatz, and Dr. Ted Achacoso break down how creatine functions as a critical cellular battery buffer. Join us as we delve into: How creatine bypasses the "methylation tax" by saving the body…
Understanding Toxicity Through Health Optimization Medicine | HOMe Podcast #009
Ep 9 · May 6, 2026 · 15 min
In this episode of the HOMe Podcast, Dr. Scott Sherr, Dr. Ted Achacoso, Dr. Jup Kuipers, and Dr. Allen Bookatz explore a foundational principle of Health Optimization Medicine: What's toxic to the cell is toxic to every organ. Through real clinical cases — including mercury toxicity, arsenic exposure, and environmental toxin accumulation — the team reveals how modern medicine often misses the root cause of disease by focusing on isolated organ systems instead of cellular function. From chronic l…
The Trust Crisis in Healthcare (And How to Fix It) | HOMe Podcast #008
Ep 8 · Apr 29, 2026 · 47 min
In this episode of the Health Optimization Medicine Podcast, Dr. Scott Sherr sits down with JJ Virgin — nutrition expert, bestselling author, and founder of the Health Business Growth Collective — to explore how healthcare practitioners can build trust, authority, and impact in today's rapidly evolving landscape. With the rise of AI and what JJ calls a "trust recession," the traditional ways of building a practice are no longer enough. Instead, practitioners must learn how to stand out as a trus…
Mental Health Starts at the Cellular Level | HOMe Podcast #007
Ep 7 · Apr 22, 2026 · 28 min
In this episode of the Health Optimization Medicine Podcast, Boomer Anderson, Dr. Ted Achacoso, Dr. Scott Sherr, and Jodi Duval explore mental health through the lens of health optimization medicine. Rather than viewing mental health as a set of diagnoses, the conversation reframes it as a function of cellular health — where brain function is driven by mitochondrial performance, inflammation, nutrient status, and environmental inputs. From neurotransmitter imbalances to brain inflammation and th…
The Cell Danger Response Explained (Why You're Not Healing) | HOMe Podcast #006
Ep 6 · Apr 15, 2026 · 37 min
In this episode of the Health Optimization Medicine Podcast, join Boomer Anderson, Dr. Ted Achacoso, and Jodi Duval as they break down one of the most important frameworks in Health Optimization Medicine — the Cell Danger Response (CDR). Originally developed by Dr. Robert Naviaux, the Cell Danger Response explains how cells respond to threat, adapt for survival, and either resolve or become "stuck" — leading to chronic disease. This episode walks through the three stages of the CDR, how mitochon…
Microglia, Metabolism & the Future of Brain Health | HOMe Podcast #005
Ep 5 · Apr 8, 2026 · 59 min
In this episode of the Health Optimization Medicine Podcast, Dr. Scott Sherr is joined by renowned neurologist and bestselling author Dr. David Perlmutter to explore one of the most important breakthroughs in brain health — the role of microglia. Often overlooked, microglial cells are the brain's immune system and play a central role in determining whether the brain thrives or degenerates over time. Dr. Perlmutter explains how these cells can shift between protective (M2) and destructive (M1) st…
The Science of Chronobiology & Health Optimization | HOMe Podcast #004
Ep 4 · Apr 1, 2026 · 24 min
In this episode of the Health Optimization Medicine Podcast, join Boomer Anderson, Dr. Ted Achacoso, Dr. Allen Bookatz, and Jodi Duval as they explore chronobiology — and how modern life is disrupting the body's natural rhythms. From jet lag and shift work to late-night scrolling and irregular meals, the conversation dives into what Dr. Ted calls "circadian pollution" — the mismatch between our biology and the environments we've created. More importantly, the team breaks down simple, powerful to…
Health vs Disease Markers: What Doctors Miss | HOMe Podcast #003
Ep 3 · Mar 25, 2026 · 24 min
In this episode of the Health Optimization Medicine Podcast, join Boomer Anderson, Jodi Duval, Dr. Allen Bookatz, and Dr. Ted Achacoso as they explore the future of clinical intelligence — and why medicine must move beyond single biomarkers to understanding networks within the body. Rather than chasing isolated lab values like glucose, cholesterol, or testosterone, the conversation shifts toward a systems-based approach — where every biomarker is part of a dynamic network of relationships. From…
The Biology of Comfort and Why We Need Stress | HOMe Podcast #002
Ep 2 · Mar 18, 2026 · 32 min
In this episode of the Health Optimization Medicine Podcast, join Dr. Scott Sherr, Dr. Ted Achacoso, Dr. Allen Bookatz, and Jodi Duval as they explore the hidden cost of convenience and comfort in modern life. From ultra-processed foods and low-fiber diets to sedentary lifestyles and technology-driven comfort, the conversation dives into how convenience is quietly reshaping our biology. The HOMeHOPe Faculty explains why small daily habits — like eating whole foods, moving regularly, and embracin…
What Is Health Optimization Medicine? | HOMe Podcast #001
Ep 1 · Mar 11, 2026 · 31 min
In this episode of the Health Optimization Medicine Podcast, the HOMeHOPe Faculty comes together for a roundtable conversation exploring the core philosophical framework behind Health Optimization Medicine. Dr. Scott Sherr, Boomer Anderson, and Dr. Allen Bookatz break down the three fundamental perspective shifts that redefine how we think about health, disease, aging, and the human body itself. Rather than focusing on disease management, this episode introduces the foundational principles behin…
Dr. Helen Messier on AI, Epigenetics & the Future of Aging | SNH Podcast #165
Ep 165 · Mar 4, 2026 · 1 hr 20 min
In this episode of the Smarter Not Harder Podcast, Dr. Helen Messier joins Dr. Scott Sherr for a wide-ranging and thought-provoking conversation about longevity, epigenetics, AI-powered medicine, and the real meaning of healthspan. From whole genome sequencing to digital twins and emotional resilience, this episode bridges cutting-edge science with deeply human healing in a way that challenges how we think about aging. Join us as we delve into: The difference between lifespan and healthspan — an…
52 Years in Nutritional Medicine with Dr. Alan Gaby | SNH Podcast #164
Ep 164 · Feb 25, 2026 · 1 hr 5 min
In this episode of the Smarter Not Harder Podcast, Dr. Alan Gaby joins Jodi Duval to explore over five decades of clinical experience in nutritional medicine. From vitamin C and magnesium to hidden food allergies and the Myers' Cocktail, this conversation unpacks what actually works — and why much of it is still ignored by conventional medicine. Join us as we delve into: • Why magnesium may be the most overlooked nutrient deficiency • Folic acid vs. methylfolate — what the research really says •…
Dr. Linda Kiley: Bladder Health, Peptides & Pelvic Repair | SNH Podcast #163
Ep 163 · Feb 18, 2026 · 1 hr 5 min
In this episode of the Smarter Not Harder Podcast, Dr. Linda Kiley joins Dr. Scott Sherr for a groundbreaking conversation on functional urogynecology — exploring the real causes of pelvic and bladder pain that most conventional models miss. Dr. Kiley shares how she uses muscle exams, peptide protocols, and root-cause diagnostics to treat conditions like interstitial cystitis, chronic UTIs, pelvic floor dysfunction, and endometriosis — often without surgery or long-term antibiotics. If you or so…
Grace Hawkins on Personalized Health & Hidden Root Causes | SNH Podcast #162
Ep 162 · Feb 11, 2026 · 1 hr 5 min
In this episode of the Smarter Not Harder Podcast, Grace Hawkins joins Jodi Duval to share her inspiring journey from medical misdiagnosis to becoming a personalized health mentor. With a background in naturopathy and clinical diagnostics, Grace blends DNA, blood chemistry, and HTMA testing to help her clients uncover the root causes of dysfunction and reclaim agency in their health journey. From endometriosis and burnout to lab interpretation and emotional patterns, this episode is a roadmap fo…
The New Rules for Aging Better, Smarter, and Sharper | SNH Podcast #161
Ep 161 · Feb 4, 2026 · 1 hr 3 min
In this episode of the Smarter Not Harder Podcast, Dr. Amanda Wiggins joins Jodi Duval to explore one of the most promising frontiers in longevity and neuroscience: brain vascular health. From her discovery of CGP (cyclic glycine-proline) to the science behind neurovascular aging, Dr. Wiggins explains why capillaries, inflammation, and even insulin play a much bigger role in dementia than most people realize. From biotech insights to personal stories, this conversation reveals what we can all do…
Redox Before Detox: Ryan Carter's Health Philosophy | SNH Podcast #160
Ep 160 · Jan 28, 2026 · 57 min
In this episode of the Smarter Not Harder Podcast, Ryan Carter joins Dr. Scott Sherr for a refreshingly real, honest, and grounded conversation about what's broken in the "biohacking" and health optimization world — and how to fix it. Ryan, a UK-based remote health practitioner, shares his journey from extreme protocols and burnout to balanced clinical systems that support long-term health. From redox before detox to seasonal eating, mold, light, water, and remote testing, this is the practition…
Dr. Libby Weaver on the Forgotten Supernutrient | SNH Podcast #159
Ep 159 · Jan 21, 2026 · 49 min
In this episode of the Smarter Not Harder Podcast, Dr. Libby Weaver joins Jodi Duval for an illuminating conversation about iron — the most overlooked yet essential nutrient for mood, cognition, metabolism, and long-term health. Together, they break down myths, lab test pitfalls, supplement confusion, and why so many women and children remain iron-deficient despite "normal" results. From hepcidin and hormone shifts to sport, anxiety, and pregnancy, this is the deep dive into iron you didn't know…
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