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Every episode
The Dr. Gabrielle Lyon Show
30 episodes
Why You're So Bloated on Ozempic
Ep 227 · Aug 13, 2026 · 14 min
You might think the number dropping on the scale is the whole win, but on a GLP-1, a meaningful share of what you're losing may be muscle, not fat, and the fiber that's supposed to help can quietly make things worse. In this solo episode, Dr. Gabrielle Lyon discusses: Why 25–40% of the weight lost on GLP-1 medications can be lean mass, and how to protect your muscle with adequate protein (1.2–1.5 g/kg) and resistance training The GLP-1 fiber paradox and why these drugs need fiber to work, but ma…
Taryn Smith - The Crash Nobody Warns You About After a Huge Win
Ep 226 · Aug 11, 2026 · 1 hr 30 min
You'd think fear is what stops you from doing hard things. At 25, with zero rowing experience, Taryn Smith crossed the Atlantic alone. 3,000 miles, 46 days, and I learned that the fear was never the obstacle. It was the signal she was finally in the right place. In this episode, Dr. Gabrielle Lyon and Taryn Smith discuss: Why fear is a "metric of success," not a stop sign, and how to train yourself to move toward discomfort instead of away from it How food becomes visible performance fuel when y…
What Glyphosate Does to Your Body
Ep 225 · Aug 6, 2026 · 21 min
You've probably worried that the glyphosate on your bread is slowly harming you. The evidence points somewhere far less obvious and far more fixable. In this solo episode, Dr. Gabrielle Lyon discusses: Why the real concern isn't cancer risk from your toast, but glyphosate's effect on your gut, where it can act like a selective antibiotic, hitting beneficial bacteria while sparing the harmful ones Where the residue concentrates (grains and legumes like oats up to 1100 ppb) and why meat, milk, and…
Juliet and Dr. Kelly Starrett - Your Back Pain Isn't Your Back
Ep 224 · Aug 4, 2026 · 1 hr 31 min
Most people think low back pain means something is wrong with their back. It's usually the hips — and the fix often starts on your living room floor. In this episode, Dr. Gabrielle Lyon sits down with Dr. Kelly Starrett and Juliet Starrett, JD to discuss: Why 100% of the people who fly across the country to get a consult for stubborn low back pain are missing hip extension, and how to test yours with the couch stretch The "injury vs. incident" framework that tells you when pain needs a doctor an…
DON'T Inject What You Can't Verify: Compounded Peptide Safety Explained
Ep 223 · Jul 30, 2026 · 25 min
Over 500 published papers stand behind one of the internet's most popular peptides, but fewer than 30 of the humans studied are in them. Dr. Gabrielle Lyon separates the molecule from the marketplace so you can tell real evidence from good marketing. In this solo episode, Dr. Gabrielle Lyon discusses: Why BPC-157's "mountain of evidence" collapses to a 99.7% animal-to-human ratio - 544 papers, but fewer than 30 humans across three uncontrolled pilot trials How to place any peptide on the spectru…
5 Hidden Causes of Bone Loss (#4 Is a Shock) - Dr. Douglas Lucas
Ep 222 · Jul 28, 2026 · 1 hr 19 min
Everyone on a GLP-1 is watching the scale; almost no one is watching their bones. Bone loss isn't an inevitable part of aging; it's a reversible signal that something deeper is going wrong, and it starts far earlier than most people are ever warned. In this episode, Dr. Gabrielle Lyon sits down with Dr. Douglas Lucas, a former Stanford-trained orthopedic surgeon turned bone-health specialist, to discuss: Why bone loss begins around 45 during perimenopause, not 50, and why waiting for your first…
The Hidden Meat Allergy Millions Don’t Know They Have
Ep 221 · Jul 23, 2026 · 25 min
You've eaten red meat your whole life, so why does a steak dinner suddenly leave you covered in hives at 1 AM? A single Lone Star tick bite can rewire your immune system into a delayed allergy to red meat, and most people (and even their doctors) never connect the two. In this solo episode, Dr. Gabrielle Lyon discusses: Why alpha-gal reactions are delayed 2–6 hours after eating meat, and how that delay causes ER visits to be repeatedly misdiagnosed How your blood type changes your risk (type A a…
GLP-1's Dark Side No One Warns You. What Rapid Weight Loss Does to Your Face and Skin - Dr. Kristy Hamilton
Ep 220 · Jul 21, 2026 · 1 hr 18 min
Everyone celebrates the weight GLP-1s take off, almost no one warns you about the volume they quietly pull out of your face and the loose skin you can't train away. The fix depends entirely on the diagnosis, and knowing which category your concern falls into is what saves you time, money, and regret. In this episode, Dr. Gabrielle Lyon sits down with Dr. Kristy Hamilton, a board-certified plastic surgeon, to discuss: Why rapid GLP-1 weight loss deflates facial volume and creates loose skin and w…
Is Your Protein Aging You? What the Longevity Science Gets Wrong
Ep 219 · Jul 16, 2026 · 33 min
The longevity world has convinced a generation of women that protein is shortening their lives. The science says they've got it backwards and the people hurt most are the ones who need protein most. In this episode, Dr. Gabrielle Lyon breaks down the protein-and-longevity fear, steelmans the strongest case against protein, then walks through what the evidence shows: The RDA (0.8 g/kg) is a deficiency floor, not a target, the intake one camp calls "dangerously high" is what federal guidelines and…
Dr. Peter Hotez - 1 in 20 Americans Has This Parasite and Doesn't Know It!
Ep 218 · Jul 14, 2026 · 46 min
The parasites most Americans think of as a tropical problem are already here; showing up as fatigue, asthma, and gut issues that standard tests keep calling "normal." An estimated 1 in 20 people may carry one and never know it. In this episode, Dr. Gabrielle Lyon sits down with Dr. Peter Hotez, a tropical-medicine physician and vaccine scientist, to discuss: Why toxocariasis, a worm shed by household dogs and cats, may affect 5–6% of the U.S. population, with larvae migrating through the lungs a…
The Truth About Microplastics No One Is Telling You
Ep 217 · Jul 9, 2026 · 23 min
You might think microplastics are just an environmental nuisance that passes through your body, but the latest tissue studies tell a very different story. As a physician, Dr. Gabrielle Lyon breaks down where the science lands, past both the fear-mongering and the dismissiveness. In this solo episode, Dr. Gabrielle Lyon discusses: Why over 58% of patients in a landmark NEJM study had plastic embedded in their arterial plaque and the 4.5x higher risk of heart attack, stroke, and death that came wi…
Cardio vs Strength Is a Myth and the Science Proves It - Alyssa Olenick
Ep 216 · Jul 7, 2026 · 2 hr 4 min
You've been told that 10,000 steps a day is enough to keep you healthy but when it comes to your bones and your muscles, walking falls short, and the science explains exactly why. The real drivers of strength, bone density, and lasting health are load, intensity, and resistance, not just movement. In this episode, Dr. Gabrielle Lyon sits down with Dr. Alyssa Olenick, a PhD in exercise metabolism and ultramarathoner who blends endurance and strength training, to discuss: Why the "interference eff…
The Testosterone Myth Men Have Been Lied To About
Ep 215 · Jul 2, 2026 · 25 min
You were told your testosterone is "normal" so why do you still feel exhausted, weak, and off? The number on your lab report was never built for you, and your own genetics may be the reason it doesn't match how you feel. In this solo episode, Dr. Gabrielle Lyon discusses: Why the standard 300–1000 ng/dL range ignores your age, comorbidities, and genetics, and why two men with identical labs can feel completely different How CAG repeats determine whether your body "catches" the testosterone you p…
Is the Protein RDA Too Low for You? What 40 Years of Studies Show - Dr. Don Layman & Dr. Heather Leidy | GLS #214
Ep 214 · Jun 30, 2026 · 1 hr 57 min
The July Forever Strong Foundations Challenge begins July 6, 2026. This 4-week challenge is designed to help you build a stronger, more energized you through sustainable nutrition, training, and lifestyle habits. Register here: https://bit.ly/4gCmoNR For 40 years you've been told 0.8 grams of protein per kilogram is "enough" but the scientists who contributed the reports behind the new 2025–2030 Dietary Guidelines say not a single study has ever shown that number beats eating more. In this episo…
Nobody Tells You What GLP-1s Do to Your Sex Drive | GLS #213
Ep 213 · Jun 25, 2026 · 38 min
The receptor that switches off your appetite on a GLP-1 drug is the same one wired into your reward circuitry, your hormones, and your blood vessels, which means when you turn down hunger, something else may be getting turned down too, and for most people taking these drugs, nobody ever checked. In this solo episode, Dr. Gabrielle Lyon discusses: Why the same drug class can improve sexual function in men with obesity while potentially dampening it in lean or postmenopausal women — and why the de…
Why Strength Beats Cardio After 50: Muscle, Longevity & Bone Density - Lisa Smith-Batchen
Ep 212 · Jun 23, 2026 · 1 hr 23 min
You might think more cardio is the key to aging well but Lisa Smith-Batchen, who has run 135 miles through Death Valley ten times, says it's strength that actually carries you through the decades. In this episode, Dr. Gabrielle Lyon sits down with Lisa Smith-Batchen, one of the most decorated ultra-endurance athletes in American history and a 10-time Badwater 135 finisher, to discuss: Why being strong matters more than being fast and why "it's not the running that helps me run, it's being strong…
Laura Horvath, Chris Hinshaw & James Sprague: What Separates Champions From Everyone Else
Ep 211 · Jun 18, 2026 · 13 min
What does it actually mean to win at the highest level? In this powerful compilation, I’m with 2024 CrossFit Games champion James Sprague, 2023 CrossFit Games champion Laura Horvath, and legendary endurance coach Chris Hinshaw to unpack the mental game behind elite performance, the vulnerability that follows victory, and why champions are often more fragile in the moments just after they win. What does winning mean to you right now? Connect with James Sprague Website: https://games.crossfit.com/…
What Your ED Is Really Telling You About Your Heart, Blood Sugar & Hormones - Urology Roundtable
Ep 210 · Jun 16, 2026 · 1 hr 33 min
Most men think erectile dysfunction is a bedroom problem and low testosterone is just a fact of getting older. This roundtable makes the case that both are early warning lights for your heart, your metabolism, and your long-term health and that ignoring them can cost you a decade. In this episode, Dr. Gabrielle Lyon sits down with urologists and men's health specialists Dr. Mohit Khera, Dr. Larry Lipshultz, and Dr. Tobias Köhler to discuss: Why a 35-year-old with ED carries a ~15% risk of heart…
How to Stay Calm in a Crisis and Why Detachment Is a Trainable Skill - Jamie Cochran
Ep 209 · Jun 9, 2026 · 1 hr 27 min
Your ego isn’t the enemy, but if you’re not actively controlling it, it is running your team, your home, and your most important relationships. Jamie Cochran, COO of Echelon Front, has spent 13 years helping leaders fix the root cause most of them never look for. The Women’s Leadership Assembly live event runs January 5–7, 2027 in Palm Springs. A free monthly webinar series runs year-round. More details here: https://events.echelonfront.com/product/assembly-004/?utm_source=google&utm_medium=cpc&…
Penis Health, What Every Man Needs to Know - Dr. Amy Pearlman
Ep 208 · Jun 2, 2026 · 1 hr 53 min
Most men think erectile dysfunction is a bedroom problem. It's actually one of the earliest warning signs of cardiovascular disease, capable of showing up three to five years before a heart attack. In this episode, Dr. Gabrielle Lyon sits down with Dr. Amy Pearlman, a urologist trained in men's sexual health, to discuss: Why ED is a symptom of vascular health, not a standalone disease and how the artery feeding the heart is roughly double the size of the one feeding the penis, so problems show u…
Your Doctor Is Watching the Wrong Number. LDL, ApoB & Heart Risk Explained. - Dr. Kevin Maki
Ep 207 · May 26, 2026 · 1 hr 25 min
Most people think the cholesterol number on their lab report tells them whether their heart is at risk. But former National Lipid Association President Dr. Kevin Maki explains that LDL is just one piece of a much bigger picture and focusing on it alone can mean missing the markers that matter most. In this episode, Dr. Gabrielle Lyon sits down with Dr. Kevin Maki, former President of the National Lipid Association and co-editor-in-chief of the Journal of Clinical Lipidology, to discuss: Why ApoB…
The Cancer Doctors Keep Missing in Young Adults - Dr. Michelle Pearlman
Ep 206 · May 19, 2026 · 2 hr 3 min
Colorectal cancer is now the leading cancer killer in adults under 50, and patients in their 20s are presenting with metastatic disease that has nothing to do with family history. Most physicians are still telling young patients with rectal bleeding that it's probably just hemorrhoids and that's costing lives. In this episode, Dr. Gabrielle Lyon sits down with Dr. Michelle Pearlman, a board-certified gastroenterologist and founder of a Miami-based gastro-metabolic clinic, to discuss: The specifi…
Jocko Willink - Parenting, Apex Kid Myth, Failure, & Leadership
Ep 205 · May 12, 2026 · 1 hr 4 min
Most parents are quietly paving the road their kids were supposed to learn to walk on by themselves and Jocko Willink has spent 20 years watching what happens when that road is too smooth. In this episode, Dr. Gabrielle Lyon sits down with Jocko Willink, retired Navy SEAL commander, founder of Echelon Front, and bestselling author of Extreme Ownership and Discipline Equals Freedom, to discuss: Why the "apex parent / apex kid" mindset is a quiet trap, and what to do instead of paving the road How…
Doctors Are Removing Testicles for This | Dr. Susan Macdonald
Ep 204 · May 5, 2026 · 1 hr 41 min
Most men don't know they have a pelvic floor, and most doctors aren't trained to look for dysfunction in it. The result: testicles are being surgically removed for pain that's actually neuropathic, at double the rate of a far more effective nerve-sparing procedure. In this episode, Dr. Gabrielle Lyon sits down with Dr. Susan Macdonald, a board-certified urologist, surgical program director at Penn State, and one of only ~30 U.S. specialists treating chronic pelvic pain in men, to discuss: Why "p…
Mark Bell on Fat vs. Carbs, What’s Really Making You Fat?
Ep 203 · Apr 28, 2026 · 1 hr 20 min
Most people are chasing the wrong version of strength and paying for it with pain, poor movement, and a body that breaks down faster than it should. In this episode, Dr. Gabrielle Lyon sits down with Mark Bell, elite powerlifter, entrepreneur, and founder of Slingshot, to discuss: Why strength training is essential at every age but most people are defining "strength" too narrowly How modern life has created an "exercise deficiency," and why artificial exercise is the only fix The truth about fat…
GLP-1 Side Effects, Risks, And Who Should Actually Be Using It | Dr. Christle Guevarra
Ep 202 · Apr 21, 2026 · 1 hr 23 min
We are living through one of the most significant shifts in medicine in generations, and most people don’t fully understand what it means. Dr. Christle Guevarra joins me to zoom out on the entire GLP-1 landscape; from the drug’s origins as a modest diabetes treatment in 2005 to today’s third-generation medications still moving through clinical trials, and what all of it means for the future of obesity, performance, and longevity. 🙌Thank you to our sponsors: 🌍 Cozy Earth - Go to https://bit.ly/…
Dominique Sachse on Aging Well, HRT, and Building Muscle After 50
Ep 201 · Apr 14, 2026 · 1 hr 21 min
The moment you decide to show up publicly, you open the door to opinions from people who would never say those things to your face. Dominique Sachse, journalist, author, and content creator who has lived her life on camera for over three decades, gets honest about what it costs to put yourself out there, why online cruelty is a psychology problem more than a content problem, and how “Teflon Dom” developed the thick skin to let none of it redirect her. Want ad-free episodes? Subscribe to Forever…
The Truth about Saturated Fat, Omega-3 Fatty Acids and Total Mortality | Dr. Tom Brenna
Ep 200 · Apr 7, 2026 · 1 hr 32 min
Only nine scientists were asked to advise on the 2025 Dietary Guidelines for Americans, and Dr. Tom Brenna was one of them. In this conversation, he pulls back the curtain on how dietary guidelines are actually made, why the process has never been the same twice, and what it was like to watch a decades-old saturated fat recommendation get carried forward despite a lack of evidence supporting it at the level of total mortality. This is the dietary guidelines conversation the internet has been mis…
GLP-1 Drugs & Bariatric Surgery Explained by a Top Obesity Researcher | Dr. David Allison
Ep 199 · Mar 31, 2026 · 1 hr 35 min
In a world flooded with conflicting health advice, how do you actually figure out what’s true? Dr. David Allison, one of the most rigorous scientific minds in obesity and nutrition research, shared the exact framework he uses to evaluate evidence, from peer-reviewed trials to podcast recommendations to AI-generated summaries. He explains the difference between trusting science as a process and trusting individual studies, why most nutrition epidemiology functions more like advertising than resea…
Dr. Tommy Wood: Can Cognitive Decline Be Reversed?
Ep 198 · Mar 24, 2026 · 1 hr 30 min
Up to 70% of dementia may be preventable, so why aren’t more people talking about what actually drives cognitive decline? In this episode, I’m with Dr. Tommy Wood, neuroscientist and author of “The Stimulated Mind,” to explore the lifestyle levers that protect your brain across a lifetime. Learn how white matter hyperintensities develop and whether they can reverse, what MCTs and ketones actually do for a glucose-starved brain, and why social connection may be the most underrated variable in cog…
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