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Every episode
Extend Podcast with Darshan Shah, MD
30 episodes
190. Dr. William Harris: 90% of Americans Are Low in This Critical Longevity Nutrient
Aug 13, 2026 · 58 min
What if one of the most important markers for your heart, brain, and longevity is something most people have never measured? AND roughly 90% of Americans aren't in the optimal range for? In this episode, I sit down with Dr. William Harris, one of the world's leading experts on Omega-3 fatty acids and the co-inventor of the Omega-3 Index, a test he helped develop more than 20 years ago. Dr. Harris has spent decades researching how omega-3s influence cardiovascular health, inflammation, cognitive…
189. Dr. Florence Comite: The 5 Biomarkers That Predict How You'll Age
Aug 11, 2026 · 36 min
What if aging isn't something you simply accept - but something you can measure, predict, and even reverse? Most of us are told our lab work is "normal," yet chronic disease often develops silently for years before symptoms appear. Dr. Florence Comite, one of the world's leading pioneers in precision medicine, is explaining why conventional medicine often misses the earliest signs of diesease- and how personalized data can completely change your health trajectory. Drawing from more than three de…
188. James Beshara: How to Find Productivity Without the Hustle
Aug 6, 2026 · 1 hr 7 min
We're living in a culture that celebrates being busy. More coffee. More hours. More hustle. But what if those things are actually making you less productive? The truth is, many high performers are stuck in a cycle of chasing energy instead of creating it. We rely on caffeine to wake up, push through stress, and squeeze more into each day - only to end up burned out, distracted, and wondering why success still feels exhausting. My guest James Beshara, is an entrepreneur, angel investor, and found…
187. Dr. Izabella Wentz: 30+ Root Causes Behind An IBS Diagnosis
Ep 187 · Aug 4, 2026 · 59 min
Hashimotos isn't just a thyroid disease-it may actually begin in the gut. If you've been told your thyroid labs are "normal" but you still struggle with fatigue, bloating, constipation, IBS, or autoimmune symptoms, this episode could change the way you think about your health. I sit down with Dr. Izabella Wentz, PharmD-better known as the Thyroid Pharmacist and one of the world's leading experts on Hashimoto's disease - to uncover the powerful connection between gut health, autoimmune disease, a…
186. Raj Sisodia: The Inner Work Behind Better Leadership
Jul 30, 2026 · 1 hr 9 min
A leader's unresolved pain rarely stays contained within that leader. It can show up as control, aggression, emotional distance, relentless pressure, or a workplace where people are treated as resources rather than human beings. The organization may still perform, but the cost is often carried by employees, families, customers, and the leader's own health. In this episode of Extend, I sit down with Raj Sisodia to examine the relationship between personal healing and conscious leadership. We disc…
185. Dr. Neha Sangwan: The 5 Questions That Predict a Health Crisis Before It Happens
Jul 28, 2026 · 53 min
I have operated on patients whose bodies had been sending them warning signals for years before a crisis ever put them in front of me. Stress alone causes or worsens more than 80 percent of the illness I see, and most of it traces back to one skill almost nobody was ever taught: how to actually listen to their own body. We dive deeper into this in the Extend Podcast with Dr. Neha Sangwan. We also chat about the five questions she asks every patient before sending them home, why your boss has mor…
184. Dr. Sahil Chopra & Sagar Chopra: Why Your Sleep Apnea Machine Might Be Lying to You
Ep 184 · Jul 23, 2026 · 1 hr 6 min
Millions of people wear a CPAP machine every night, the standard breathing device prescribed for sleep apnea. They trust the number on the screen to tell them their sleep apnea is under control. I've had patients tell me they stopped using theirs because it felt pointless, and it turns out that feeling was often correct. We dive deeper into this in this episode of Extend with Dr. Sahil Chopra and Sagar Chopra, co-founders of Empower Sleep. We also chat about why palate shape and mouth breathing…
183. Rachel Lambert & Angie Noack: Why 70% Of ADHD Diagnoses Are Wrong
Jul 21, 2026 · 54 min
For most people, an ADHD diagnosis, an anxiety diagnosis, or a depression diagnosis is made entirely from a symptom checklist. No one looks at the brain producing those symptoms. In this episode, I sit down with Rachel and Angie, co-founders of BrainCode Centers, to talk about quantitative EEG brain mapping and neurofeedback, and why measuring the brain's actual electrical activity changes the picture so often. We look at why the majority of people carrying an ADHD diagnosis do not show the neur…
182. Michael Easter: The Hidden Health Cost of Modern Comfort
Jul 16, 2026 · 58 min
A lot of people do not need to be convinced that the stairs are better than the escalator, walking is better than sitting all day, and reaching for the phone every quiet second is probably not helping their focus. The harder question is why the easier option still wins so often, even when someone cares about their health. This episode starts there, with the strange gap between what we know is good for us and what modern life quietly trains us to choose. In this episode of Extend, I sat down with…
181. Dr. Taz: The Hormone Conversation Women Should Have Before Birth Control, IVF, or HRT
Jul 14, 2026 · 50 min
For many women, the hormone conversation starts only when something becomes hard to ignore. Painful periods. Irregular cycles. Acne. Hair loss. Fertility struggles. Perimenopause symptoms. Too often, the answer is a quick fix for the symptom in front of them, without anyone asking what the body was trying to signal years earlier. In this episode, I sit down with Dr. Taz Bhatia MD to talk about why women's hormone health needs to be understood across the entire lifespan, not as separate problems…
180. Dr. John Kim: The Hidden Stressors Keeping Your Body in Defense Mode
Jul 9, 2026 · 57 min
When labs look normal, it is easy to assume the body is fine or that the biggest risks have been ruled out. Dr. John Kim's story challenges that belief. At 33, after a normal lipid panel and without the classic heart attack picture, he ended up with an 85% blockage in his LAD. That experience forced him to ask what standard markers were missing. The answer led him into the deeper cellular stressors that can keep the body in defense mode: mold, mycotoxins, chronic infections, biofilms, heavy meta…
179. Dr. Scott McMahon: The Hidden Trigger Behind Your Unexplained Symptoms
Ep 179 · Jul 7, 2026 · 46 min
Most people assume that once they leave a mold-exposed building, their body should recover. But I see this all the time in my clinic, the mold exposure ends, and the symptoms don't. In this episode of Extend, I sit down with Dr. Scott McMahon, medical director at MoldCo, to ask why removing the source doesn't always mean removing the illness. We get into a switch inside the immune system, one that determines whether the body can actually call off an inflammatory response once a threat is gone, a…
178. Dr. Matt Kaeberlein: The Science, Risk, and Hype Behind Today's Longevity Trends
Jul 2, 2026 · 1 hr 14 min
If you care about longevity, you have probably seen the same pattern over and over again. A new peptide, supplement, biological age test, off-label drug, or protocol starts gaining attention, and suddenly it sounds like the missing piece everyone should be using. The hard part is not wanting to be proactive. The hard part is knowing which claims have real evidence behind them, which ones are still early signals, and which ones may carry risks no one is measuring carefully enough. In this episode…
177. Dr. Jila Senemar: The Hormone Conversation Women Should Have Before Menopause
Jun 30, 2026 · 42 min
A lot of women are taught to think about hormones only when something becomes impossible to ignore. Painful periods. Birth control decisions. Fertility anxiety. Postpartum changes. Perimenopause symptoms. Menopause. But what if those are not separate conversations? What if the body has been giving clues for years before the symptoms become loud enough to finally get attention? In this episode, I sit down with Dr. Jila Senemar to look at women's hormone health through a much wider lens. We talk a…
176. Dr. Labib Ghulmiyyah: What Fertility Can Reveal About Your Long-Term Health
Jun 25, 2026 · 57 min
When a couple is trying to get pregnant and it is not happening, the conversation can become very intense very quickly. Suddenly, you are hearing about IVF, egg freezing, AMH, sperm count, hormones, age, cost, and timing. But before the conversation jumps straight to the next procedure or the next number to panic over, there may be a deeper question worth asking: What is fertility trying to tell us about the health of the mother, the father, and the future child? In this episode of Extend, I sit…
175. Justin Roethlingshoefer: Why Your Body Needs More Than "Healthy Habits" To Heal
Jun 23, 2026 · 53 min
Your body is constantly repairing, renewing, and rebuilding itself. Hundreds of millions of cells are replaced every few months, which sounds incredible until you ask the question most people skip: if the body is designed to heal, why do so many people still feel tired, foggy, inflamed, slow to recover, or like something is off even when they are doing so many of the "right" things? In this episode of Extend, I sit down with Justin Roethlingshoefer to bring that question back to the cell. Justin…
174. Dr. Dave Rabin: Why Being Human Feels Harder Than It Should in 2026
Jun 18, 2026 · 1 hr 1 min
A lot of people are trying to do the right things. They are learning more, tracking their health, working on their stress, trying to be more present, and using the tools they have been told should help. But if the advice is available, the science is clearer than ever, and the tools are right in front of us, why do so many people still feel overwhelmed, burned out, disconnected, or unable to make those changes stick? In this episode of Extend, I sit down with Dr. Dave Rabin to talk about one of t…
173. Brian Le Gette: The Hidden Reason Your Body Struggles To Heal
Jun 16, 2026 · 60 min
When your body feels wired, depleted, foggy, inflamed, or slow to recover, the usual instinct is to add something else. Another supplement. Another device. Another protocol. But the body does not respond to tools just because they are available. It responds to the signals it is receiving, and if those signals keep telling the body it is under threat, it will keep prioritizing survival over repair. In this episode of Extend with Dr. Shah, I sit down with Brian Le Gette, the creator of the Ammorta…
172. Dr. William Von Hippel: The Connection-Autonomy Paradox: Why More Freedom Can Make Us Feel More Alone
Jun 11, 2026 · 51 min
Modern life tells us that more freedom should make us happier. More independence, more control, more convenience, more space to do life on our own terms. But what if the thing we keep chasing is also the thing quietly pulling us away from what our brain and body still need most: connection. In this episode of Extend, I sit down with Dr. William Von Hippel to talk about the conflict between two of our most basic human motives: connection and autonomy. We get into why connection used to be built i…
171. Dr. Kristen Holmes: The Sleep Debt Problem Affecting Your Brain, Mood, and Relationships
Jun 9, 2026 · 59 min
Sleep debt is usually treated like a personal problem. You sleep less, feel tired, and try to catch up later. But Dr. Kristen Holmes explains why that belief is too small. When your body is missing the sleep it actually needs, it can affect your mental control, emotional regulation, leadership, and even how safe the people around you feel in your presence. In this episode of Extend, I sit down with Dr. Kristen Holmes to talk about recovery in a way that goes far beyond "just sleep more." We get…
170. Dr. Sonya Jensen: The Hormone-Trauma Connection: Why Midlife Symptoms Are Not Just Physical
Jun 4, 2026 · 57 min
Hormone symptoms are usually treated like a problem with levels. Progesterone is low. Estrogen is shifting. Cortisol is high. Testosterone is dropping. So the conversation often becomes about what to replace, what to supplement, or what protocol to follow. But there is a deeper layer that rarely gets brought into the room: the body is also responding to the stress, grief, resentment, trauma, people-pleasing, perfectionism, and survival patterns it has been carrying for years. In this episode of…
169. Natalie Lefevre: How to Find the Toxins Blocking Your Body's Ability to Heal
Jun 2, 2026 · 47 min
You can do the supplements, the IVs, the sauna, the clean eating, and the wellness routine, but if your body is still being exposed to toxins every day, you may be cleaning up a mess while the tap is still running. That is what makes toxic load so frustrating. It can hide in your water, food, air, dental work, travel habits, mold exposure, heavy metals, PFAS, pesticides, microplastics, and even the products you use daily, while standard labs never show the full picture. In this episode of Extend…
168. Peter Crone: Why You Can't Access True Vitality Until You Free Your Mind
May 28, 2026 · 56 min
When we talk about health, longevity, and performance, the conversation often starts with the body. We look at biomarkers, sleep, nutrition, exercise, recovery, and protocols, hoping that if we get enough of the physical pieces right, we will finally feel better, stronger, and more alive. Yet there is another layer that can quietly shape everything from the way we handle stress to the way we heal, lead, love, perform, and experience our own potential. In this episode of Extend, I sit down with P…
167. Dr. Amie Hornaman: The Thyropause Problem: Why So Many Women Feel Off in Midlife Despite "Normal" Labs
Ep 167 · May 26, 2026 · 56 min
Have you entered midlife and started gaining weight, feeling exhausted, waking up foggy, losing motivation, or noticing your mood shift while your labs keep coming back "normal"? For a lot of women over 40, that answer does not bring relief because they still feel off, and this episode explains why thyropause, the midlife decline in thyroid function, is so often missed, dismissed, or mistaken for aging, burnout, depression, or menopause. We dive deeper into this in the Extend Podcast with Dr. Da…
166. Carolina Reis de Oliveira: The Missing Link Between Skin and Longevity
Ep 166 · May 21, 2026 · 57 min
If you think your skincare routine is protecting your skin, this conversation may make you look at your bathroom shelf differently. You've been taught to treat your skin like something cosmetic, something you maintain for how it looks. But your skin is your largest organ, it has its own biological age, and if you are not supporting it properly, it can become a constant source of inflammation and damage that goes far beyond appearance. We dive deeper into this in Extend with Carolina Reis de Oliv…
165. Cynthia Thurlow: The Menopause Gut - Why Healing Your Hormones Starts With Healing Your Gut
May 19, 2026 · 1 hr 5 min
The gut and hormones have always been treated as two completely separate conversations in medicine, and that disconnect is quietly behind some of the most frustrating symptoms women experience in midlife. From bloating and brain fog to autoimmune conditions and weight that will not move, the answers have been there all along, hiding in a connection nobody thought to make. We dive deeper into this in the Extend Podcast with Cynthia Thurlow. We also talk about why perimenopause is the ultimate lit…
164. SXSW Panel: How To Actually Take Control Of Your Health In 2026 and Beyond
Ep 164 · May 14, 2026 · 56 min
A lot of us are doing everything we can to stay healthy, taking supplements, wearing trackers, getting our labs done, and still ending up sick. And if you are like most people, you probably thought that was on you, that you were not disciplined enough, not consistent enough, or simply not doing the right things, but that is not the case. The system we have been relying on was never designed to keep us well in the first place, and expecting the Western medical system to manage your long term heal…
163. Steve Chua: How Your Identity Is Either Healing Or Destroying Your Health
Ep 163 · May 12, 2026 · 1 hr
Most high performing executives will spend thousands optimizing their glucose levels, their sleep, and their body composition without ever stopping to ask why none of it makes them feel any better. The answer almost never lives in their labs and it almost never lives in their training program. It lives in the identity they built their entire career on top of, and the silent narrative driving every decision they make, that tells them their worth is only as good as their last result. In this episo…
162. Dr. Meredith Broderick: What An Undiagnosed Sleep Disorder Is Quietly Doing To Your Brain And Body
Ep 162 · May 7, 2026 · 1 hr 15 min
A lot of people are walking around exhausted, foggy, moody, and struggling with their cardiovascular health blaming stress, diet, age, and everything in between, never once considering that the real culprit might be happening in the eight hours they are not even awake for. And in children, what is being labeled as ADHD and treated with medication could in many cases simply be an undiagnosed sleep disorder that nobody thought to look for. In this episode of Extend, I sit down with Dr. Meredith Br…
161. McCall McPherson: Why Your Thyroid Is Being Undertested And Undertreated
May 5, 2026 · 47 min
Fatigue, brain fog, weight gain, hair loss, low libido, high cholesterol, and a doctor who keeps telling you your labs look normal. For the millions of people walking around with an undetected or poorly managed thyroid condition, this is not just a frustrating experience but a dangerous one. Because what their doctor never told them is that the most important thyroid marker, the one that actually powers every cell in the body, is only being checked 4% of the time, which means the test they are r…
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