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Every episode
Y Combinator Startup Podcast
30 episodes
Chelsea Finn: This is the State of the Art in Robotics
Aug 13, 2026 · 58 min
Robots can already fold laundry, make espresso, clean kitchens, and assemble things. The harder problem is getting them to do those tasks reliably, for long periods of time, without a human babysitting them. At Startup School 2026, Physical Intelligence cofounder Chelsea Finn explains what it takes to build general-purpose robots that work in the real world. She shares how reinforcement learning pushed robot throughput up 2x, how their systems can run autonomously for hours, and why she believes…
Peter Steinberger: "Fun Is Velocity"
Aug 11, 2026 · 42 min
Last November, Peter Steinberger was annoyed that there was no good way to talk to his coding agents from his phone, so he built one himself. A few months later, OpenClaw had exploded into one of the biggest open source AI projects in the world, with nearly 3,000 contributors and a peak of 4.7 million weekly downloads.At Startup School 2026, Peter tells the story of what happened when OpenClaw took off, what he got wrong as it grew, and how he eventually stopped using the product he had built fo…
Max Hodak: How Startups Build Speed
Aug 10, 2026 · 57 min
Science is building a retinal implant that restores vision to people who have gone blind. One patient has already used it to read a 300-page novel.Building a company like that requires a lot more than getting the technology right. At Startup School 2026, Science CEO Max Hodak explains how the company buys things and hires people, and why those systems determine how fast it can move.He also gets into why founders can’t delegate their judgment, and why there’s no set of five bullet points that mak…
How To Design In The Agent Era
Aug 7, 2026 · 56 min
AI isn't just changing the tools designers use. It's changing how they build, ship, and stand out. In this episode of Design Review, Stephen Haney, founder of AI-native design tool Paper, joins YC General Partner Aaron Epstein to demo the agent-first workflow that's making Paper one of the fastest-growing design tools since Figma. Using live redesigns of user-submitted websites as examples, they break down the most common AI design tells, show how to fix them in seconds, and explain why the bigg…
Garry Tan: Own Your Intelligence
Aug 6, 2026 · 42 min
The next generation of startups will be built by smaller teams than ever before. At Startup School 2026, YC President & CEO Garry Tan explains why we're entering the era of personal AGI: AI agents that run on your own infrastructure, compound your knowledge over time, and dramatically increase your ability to build. He shares the tools and workflows he uses every day, why every founder should own their intelligence instead of renting it, and what it means to build under your own power. Transcrip…
Building the First Data Centers in Space
Aug 5, 2026 · 36 min
Philip Johnston is the co-founder and CEO of Starcloud, the company building data centers in space. In November 2025, Starcloud launched an Nvidia H100 GPU into orbit and trained the first large language model in space. They've since raised $200 million, hit a billion-dollar valuation just 17 months after YC demo day, and filed with the FCC to deploy 88,000 more satellites. In this episode, Philip walks us through their wild origin story, the engineering challenges behind the Starcloud-1, why th…
Waymo Co-CEO Dmitri Dolgov: "Move Fast And Ship Safely"
Aug 4, 2026 · 49 min
Waymo’s first autonomous demo took eighteen months. The product took fifteen years. Today, the Waymo Driver runs 500,000 trips a week — four million fully autonomous miles across fifteen cities, with 17 times fewer serious-injury crashes than human drivers. At Startup School 2026, Waymo co-CEO Dmitri Dolgov shares the seven lessons behind that journey, from bridging the gap between a demo and a real product to building systems that can safely operate in the physical world. Transcript: https://ww…
Patrick Collison: "What If You Succeed?"
Aug 3, 2026 · 31 min
In 2009, Patrick and John Collison went to Startup School in Berkeley, got sushi in Potrero Hill afterward, and decided on the walk home to start Stripe. The reasoning, as Patrick remembers it, was that “we might as well because it probably won't be that hard.” It took two years to launch. Seventeen years later, at Startup School 2026, he talks with YC's Harj Taggar about dropping out of MIT twice, why founders should ask what happens if they succeed, and what Stripe's own data says about the be…
Jeff Dean: The 1% Rule for Building in AI
Aug 1, 2026 · 57 min
In 2001, Jeff Dean and Sanjay Ghemawat did the math and realized Google’s entire search index would fit in RAM — then shipped it in a few days, and search got fast. In 2013, another napkin calculation showed that three minutes of daily speech recognition per user would require doubling Google’s server fleet. That one became the TPU. At Startup School 2026, Google’s Chief Scientist talks with YC’s Diana Hu through the thought experiments behind both, why inference hardware is the next specializat…
Alexandr Wang: “This is a Once-in-a-Civilization Opportunity”
Jul 31, 2026 · 32 min
Alexandr Wang's advice to his 18-year-old self: develop your own internal compass for how the future will unfold, and hold conviction in it against the noise. At Startup School 2026, the Scale AI (YC S16) founder — now leading Meta's Superintelligence Labs — talks with Garry Tan about rebuilding a frontier lab from scratch, why talent density compounds, and how to spot the exponential worth betting your twenties on.
Blake Scholl: Breaking the Supersonic Ban
Jul 29, 2026 · 50 min
In 1969, we landed on the moon and flew Concorde. Half a century later, we could do neither. Blake Scholl founded Boom Supersonic (YC W16), the startup building America’s first supersonic airliner, to change that. At Startup School 2026, he shares how a cardboard mockup with Office Depot seats became XB-1, the first independently developed jet to break the sound barrier, and why founders have to build for both the worst day and the best day. He also answers founder questions about teaching yours…
Sam Altman: "Never a Better Time to Do a Startup"
Jul 28, 2026 · 39 min
In 2005, Sam Altman was a Stanford sophomore in YC’s first batch, building a startup in a little Cambridge office while Paul Graham cooked the founders dinner. Twenty years later, as co-founder & CEO of OpenAI, he closed Startup School 2026 in conversation with YC's Garry Tan — on agents, ambition, and why the ceiling for what a startup can take on has never been higher.
Boris Cherny: Building Claude Code
Jul 28, 2026 · 36 min
Fresh off the launch of Opus 5, Claude Code creator Boris Cherny joins Diana Hu at Startup School 2026 to talk about what the newest models can do, how Claude Code came to be, and what it means to build products when the underlying capabilities keep accelerating.
Jensen Huang: The Mindset That Built NVIDIA
Jul 27, 2026 · 49 min
NVIDIA started with the wrong technology, learned the right one from three textbooks bought at Fry’s, and went on to invent most of the major breakthroughs in modern computing.At Startup School 2026 at Chase Center, Garry Tan sits down with Founder and CEO Jensen Huang to talk about confronting reality, learning your way into new domains, and why resilience — getting through one day at a time — matters more than anything else.
World Models, Explained
Jul 17, 2026 · 1 hr 14 min
Why do even our best AI models need tens of thousands of examples to learn skills that a human picks up in a handful of tries?Solving this problem is one of the great open challenges in modern AI. World models, which give AI an internal simulation of its environment, are one of the most promising paths forward.In this episode of Decoded, YC's Ankit Gupta and Francois Chaubard discuss the intuition and math behind world models, new research, and current applications in self-driving, robotics, and…
How To Better Understand Your Users
Jul 9, 2026 · 14 min
Most founders obsess over dashboards and aggregate metrics, but some of the best product insights come from understanding how individual users actually use their product. In this episode of Startup School, YC's David Lieb walks through one of his favorite tools for better understanding your users, the dot plot. It's a simple two-dimensional grid that reveals usage patterns no aggregate chart can show you. He’ll cover why it gives founders a better sense of product health, what patterns to look f…
Why Domain Experts Are Winning In The Age Of AI
Jun 19, 2026 · 43 min
Bryant Chou co-founded Webflow, which today powers around 1% of all websites on the internet. Now he's back in the current YC batch with Ploy, an AI-powered website and marketing platform that doesn't just build your site — it connects to your analytics, CRM, and search console to optimize your marketing while you sleep. In this episode of the Lightcone he explains how he built Ploy to be “anti slop,” how building today compares to his first startup, and why founders with domain expertise are ma…
How To Pick A Startup Idea
Jun 17, 2026 · 12 min
Many founders get stuck trying to find the perfect startup idea before they commit. But the perfect idea doesn't exist in the abstract. The only way to find what works is to pick one, go deep, and get feedback from real customers. In this episode of Startup School, YC's Jon Xu breaks down how to choose what to build, "burn the other boats," and go deep enough to practically run your customer's business— and why that depth is what surfaces the better idea underneath.
"The CEO Must Be the Chief AI Officer"
Jun 10, 2026 · 54 min
Brex co-founder and CEO Pedro Franceschi believes most people still underestimate how much AI will change the way companies are built. AI isn't just another tool, it's a new foundation for building products, teams, and companies.In this episode of Lightcone, Pedro shares why he thinks we're only months into a platform shift as significant as the invention of electricity, how AI has changed the way he works, and why every founder should be "token maxing" to understand the limits of the technology…
How to Build an AI-Native Services Company
Jun 3, 2026 · 11 min
Some of the biggest companies of the next decade won't be software businesses, they'll be services companies like insurance carriers, law firms, and tax practices rebuilt from scratch with AI doing most of the work. In this episode of Startup School, YC Visiting Partner Charlie Warren walks through the playbook for building AI native services companies, covering how to pick a market with the right traits, why variance kills these businesses faster than anything else, and the P&L math that’ll tra…
How To Build Superintelligence Inside Your Company
May 27, 2026 · 46 min
Building superintelligence inside a company isn't about adding AI as a feature. It's about making it the operating system the whole organization runs on. In this episode of the Lightcone, we sat down with YC's Pete Koomen to talk for the first time about how he led the effort to build YC's internal agent infrastructure from the ground up. We cover how giving agents unrestricted access to one database changed everything, the self-improving skill loops that get smarter overnight and why he thinks…
How The Best Companies Defend Against Mediocrity And Rot
May 25, 2026 · 50 min
In this episode of the Main Function Garry sits down with Eric Ries, author of "The Lean Startup", about his new book, "Incorruptible: Why Good Companies Go Bad And How Great Companies Stay Great". Ries breaks down why shareholder primacy often leads to company and product degradation, how founders can lose control of the companies they build, and what legal structures and governance models can protect a company's core mission from outside threats.
Paul Graham: Should you move to Silicon Valley?
May 13, 2026 · 22 min
Paul Graham is a co-founder of Y Combinator. He's funded and mentored companies like Dropbox, Airbnb, DoorDash, and thousands of others through YC, and is one of the most influential voices in the startup world. In this talk at our YC | Stockholm event last month, Paul walks through why ambitious founders should move to Silicon Valley at least briefly, what makes it uniquely valuable — from serendipitous meetings and faster investor decisions to a deeply embedded pay-it-forward culture — and why…
Tokenmaxxing: How Top Builders Use AI To Do The Work Of 400 Engineers
May 8, 2026 · 41 min
We're entering a new era of software where a single person, working with AI agents, can build products that previously required entire teams.In this episode of Lightcone, the hosts break down the rise of AI coding agents, "tokenmaxxing", and the emerging workflows behind tools like Claude Code and OpenClaw. They discuss why AI systems today feel less like productivity tools and more like collaborators, why the future of AI should be personal and user-controlled, and how founders are starting to…
Beyond Bigger Models: Recursion As The Next Scaling Law In AI
May 1, 2026 · 38 min
A 7-million parameter model outperforming models a thousand times its size on tasks like ARC Prize. That's what recursive reasoning unlocks.In this episode of Decoded, YC's Ankit Gupta and Francois Chaubard break down two recent papers on recursive AI models, HRMs and TRMs, that are achieving state-of-the-art results with a fraction of the parameters of today's largest models.They explain why standard LLMs hit a fundamental ceiling on certain reasoning tasks, how recursion at inference time give…
How to Build the Future: Demis Hassabis
Apr 29, 2026 · 41 min
Demis Hassabis has had one of the most extraordinary careers in tech. He started as a chess prodigy and video game designer at 17 before getting a PhD in neuroscience and going on to found DeepMind. His lab cracked Go, solved protein structure prediction with AlphaFold, and then gave it away free to every scientist on earth. That work won him the 2024 Nobel Prize in Chemistry. Today he leads Google DeepMind, pushing toward the same goal he set as a teenager: AGI. On this special live episode of…
The $9B Startup That Wants to Create a Billion New Developers
Apr 25, 2026 · 39 min
Replit is the leading no-code app builder for consumers and enterprise, letting anyone with an idea build real, deployed software using natural language. The company just raised a $400 million Series D at a $9 billion valuation.In this episode of Founder Firesides, co-founder and CEO Amjad Masad sat down with YC's Andrew Miklas to talk about Replit's 10-year journey from browser IDE to vibe coding platform, why the people getting the most value aren't traditional developers but founders and doma…
The Playbook For Building An AI Native Company
Apr 24, 2026 · 10 min
AI isn't just making teams more productive. It's changing how companies should be built. In this episode of Startup School, YC Partner Diana Hu explains what it means to build an AI-native company, where AI isn't just a tool but the operating system your company runs on. She breaks down how to make your company queryable so agents can improve across every function, why management hierarchies break down when an intelligence layer replaces human middleware, and why early-stage founders have a mass…
Stripe Head of Design Katie Dill Breaks Down Their New Website
Apr 22, 2026 · 44 min
Even the most successful websites eventually need a redesign. Take Stripe for example. After six years with the same homepage, they recently unveiled a brand new site that reflects how the fintech giant has evolved over the past few years. So when is the time right for a new landing page? And what should you prioritize in the redesign? In this episode of Design Review YC’s Aaron Epstein sat down Stripe’s Head of Design Katie Dill to pull the curtain back on their high profile redesign and to dis…
The GPT Moment for Robotics Is Here
Apr 16, 2026 · 49 min
Physical Intelligence is building a foundation model that can control any robot to do any task — what the team describes as the GPT-1 moment for robotics. The company's cross-embodiment approach trains across many different robot platforms, and recent results show tasks being performed zero-shot that last year required hundreds of hours of data collection. In this episode of The Lightcone, co-founder Quan Vuong sat down with Garry, Jared, Diana, and Harj to talk about why robotics is finally rea…
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