Two deformed psychopaths with completely deranged minds live in a secluded house in the woods. “Puppet Brain” kidnaps a girl, takes her to their house, and sedates her so that the other one can gut her, after which the first one roasts her entrails on a barbecue. After reveling in this, they’ll go in search of another victim not realizing that her boyfriend, who won’t listen to reason, is also out there.