'Walter Pagel's last book is more arcane and difficult, certainly as erudite and inimitable, and perhaps as rewarding as all his others. In a strange alchemical mixture of alter ego, familiar and doppelgänger, Paracelsus was Pagel's cross and his torch. ' With 'The Smiling Spleen', Walter Pagel reconfirms his position as a leading authority on Paracelsus and the influence of his doctrines and practice on the development of modern science and medicine. In this final work of his life, Pagel concentrates on Paracelsianism as a historical phenomenon, giving major attention to the lesser-known figures who characterized the 'storm and stress' of the Paracelsian reform movement during the 16th and 17th centuries.