This text offers a comprehensive treatment of the fundamental biological, chemical and epidemiological principles of metal carcinogenesis and its assay as these are presently understood. It addresses problems of human exposure, the induction of tumors in experimental animals, and the effects of metal on ""in vitro"" systems. This book should be of interest to pharmacologists, toxicologists, epidemiologists, biologist, pathologist, industrial hygienists and those needing actively to assay metals and their compounds for carcinogenicity.