With over 300 entries from the ancient abacus to X-ray diffraction, as represented by a ca. 1900 photo of an X- ray machine as well as the latest research into filmless x- ray systems, this tour of the history of scientific instruments in multiple disciplines provides context and a bibliography for each entry. Newer conceptions of "instrument" include organisms widely used in research: e. g. the mouse, drosophila, and E. coli. Bandw photographs and diagrams showcase more traditional instruments from The Science Museum, London, and the Smithsonian's National Museum of American History. Annotation copyrighted by Book News, Inc. , Portland, OR