This book constitutes the refereed proceedings of the 25th International Conference on Information Security Applications, WISA 2024, held in Jeju Island, South Korea, during August 21–23, 2024. The 28 full papers included in this book were carefully reviewed and selected from 87 submissions. They were organized in topical sections as follows: Cryptography; Network Security; AI Security 1; Network & Application Security; AI Security 2; CPS Security; Fuzzing; Malware; Software Security; and Emerging Topic.