This book constitutes the refereed proceedings of the 11th International Conference on Data Science, ICPCSEE 2025, held in Hiroshima, Japan, during September 19–21, 2025. The 41 full papers and 1 short papers included in this book were carefully reviewed and selected from 135 submissions. They were organized in topical sections as follows: Education using big data, intelligent computing or data mining, etc. ; Education research, methods and materials for data science and engineering; Machine Learning for Data Science; Basic Theory and Techniques for Data Science; Application of Blockchain; Big Data Management and Applications; Industrial Digitization and Applications; Applications of Data Science; Data Security and Privacy; Data-driven Scientific Research; and Novel methods for data analytics.