Set in California, Liars and Saints follows four generations of the Catholic Santerre family from World War II to the present, as they navigate a succession of life-altering events -- through the submerged emotion of the fifties, the recklessness and excess of the sixties and seventies, and the reckonings of the eighties and nineties. In a family driven by jealousy and propriety as much as by love, an unspoken tradition of deceit is passed from generation to generation, and fiercely protected secrets gradually drive the Santerres apart. When tragedy shatters their precarious domestic lives, it takes astonishing courage and compassion to bring them back together.